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Quick Update: Is this the End of Humanity? - Ceftriaxone and Azithromycin "Resistant" Neis

Leading photo: microbeonline.com UPDATE: they finally determined endpoint MICs CRO = 0.5 AZT > 256 This is the real deal y'all. Public Health England reported an imported case of N. gonorrhoeae infection with treatment failure (CRO only, followed by SPT) Not treated with double regimen (CRO+AZT) Genital infection was cured, but throat was persistently positive Not a surprise since throat infections are harder to get rid of, and ALL reported cases of CRO failure so far have exclusively been pharyngeal infections Caused by a bug with: CRO MIC > 0.125 EUCAST breakpoint for R: >0.125 CLSI breakpoint for R: >0.25 AZT MIC > 0.5 EUCAST breakpoint for R: >0.5 CLSI epidemiological cutoff (ECV) for NW

Quick Update: Salmonella Enteridis in Pet Guinea Pigs

https://www.cdc.gov/salmonella/guinea-pigs-03-18/index.html Involving 9 people from 8 states WGS confirmed to be related Illnesses started on dates ranging from July 17, 2015 to December 15, 2017 Same Salmonella Enteridis identified in sample from an ill person’s pet guinea pig in Vermont These rodents may be carrying Salmonella and not appear to be sick Pet rodents: NOT recommended for children <5 yo, should not be kept in childcare centers Wash your hands after touching, feeding, or caring for pet rodents or cleaning their habitats

Quick Update: Salmonella Typhimurium Outbreak Associated with Dried Coconut

Affected product Image: CDC https://www.cdc.gov/salmonella/typhimurium-03-18/index.html As of March 2018: 13 cases of Salmonella Typhimurium among 8 states, WGS confirmed as outbreak strain No death, no antibiotic resistance so far (per NARMS) Ill persons reported consumption of dried coconut product purchased from Natural Grocers stores Outbreak strain was also identified in leftover dried coconut from one of the patient's home FDA also collected dried coconut from International Harvest, Inc. and found outbreak strain in samples of International Harvest Brand Organic Go Smile! Dried Coconut Raw and Go Smiles Dried Coconut Raw If you believe you may have purchased or consumed contaminated pr

Quick update: Potential Mumps Exposure at National Cheerleading Competition

Photo: Dallas Sports Commission See article from the Washington Post: https://www.washingtonpost.com/news/early-lead/wp/2018/03/07/thousands-of-cheerleaders-may-have-been-exposed-to-mumps-at-national-competition/?utm_term=.cb22d4f12c21 Note: the CDC recommends getting a third dose of mumps vaccine (for people who have completed a 2-dose regimen) after a potential exposure in an outbreak, especially in high-risk, extended contacts. For those that have not completed the regimen, another dose is still recommended. See details in MMWR: https://www.cdc.gov/mmwr/volumes/67/wr/mm6701a7.htm?s_cid=mm6701a7_w

Quick Update 3/2/18

This year's flu vaccine effectiveness was 36% overall, 25% against H3N2, 67% against (H1N1)pdm09, and 42% against influenza B. Not that bad at all! This is interim data, BTW. https://www.cdc.gov/mmwr/volumes/67/wr/mm6706a1.htm?s_cid=mm6706a1_w Photo by Kelly Sikkema on Unsplash

PEERA HEMARAJATA, M.D., PH.D., D(ABMM)

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